BDBM706450 2-(4-(6a,7,9,10-Tetrahydropyrazino[1,2-a]Thieno [4,3,2-De]Quinolin-8 (6H)-Yl)Butyl) Isoindolin-1-One ::US20240383913, Compound I-22

SMILES O=C1c2ccccc2CN1CCCCN1CCN2c3cccc4scc(c34)CC2C1

InChI Key InChIKey=XPKCZHVPUKJNLR-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 706450   

TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

US Patent
LigandPNGBDBM706450(2-(4-(6a,7,9,10-Tetrahydropyrazino[1,2-a]Thieno [4...)
Affinity DataKi:  490nMAssay Description:The affinity of the compounds of the present disclosure for the dopamine D2 receptors was determined by the method of radioligand competition experim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandPNGBDBM706450(2-(4-(6a,7,9,10-Tetrahydropyrazino[1,2-a]Thieno [4...)
Affinity DataKi:  1.20E+3nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent