BDBM706780 6-((1R,3S)-3-(1-isopropyl-3-(5- (trifluoromethyl)pyridin-3-yl)- 1H-pyrazol-5-yl)cyclopentyl)- 2-thia-6-azaspiro[3.4]octane 2,2-dioxide::US20240398781, Example 13A

SMILES CC(C)n1nc(-c2cncc(C(F)(F)F)c2)cc1[C@H]1CC[C@@H](N2CCC3(C2)CS(=O)(=O)C3)C1

InChI Key InChIKey=OMKKJZHLVORLNY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 706780   

LigandPNGBDBM706780(6-((1R,3S)-3-(1-isopropyl-3-(5- (trifluoromethyl)p...)
Affinity DataKi:  6.90nMAssay Description:SPA: Determination of equilibrium dissociation constant Kd of radioligand: Membrane prepared as described above was pre-incubated with PVT-WGA SPA be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent

LigandPNGBDBM706780(6-((1R,3S)-3-(1-isopropyl-3-(5- (trifluoromethyl)p...)
Affinity DataKi:  15nMAssay Description:DHCR7: The radioligand binding assay was prepared by adding assay buffer diluted hEBP-DHCR7 membrane at 66.7 μg/ml×150 μl/well into the 96-well compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent