BDBM707063 6-(2-Methyl-2-(4- (trifluoromethoxy)phenoxy)propyl)- 2-thia-6-azaspiro[3.4]octane 2,2-dioxide::US20240400579, Example 136

SMILES CC(C)(CN1CCC2(C1)CS(=O)(=O)C2)Oc1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=PXMGMFOCRFCVSM-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 707063   

LigandPNGBDBM707063(6-(2-Methyl-2-(4- (trifluoromethoxy)phenoxy)propyl...)
Affinity DataKi:  14.2nMAssay Description:Compounds were prepared in a 96-well U bottom plate using an Echo550 machine and 10 mM compound DMSO stock solution, followed by an 8-dose 5-fold ser...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent

TargetEmopamil-binding protein-like(Human)
Genentech

US Patent
LigandPNGBDBM707063(6-(2-Methyl-2-(4- (trifluoromethoxy)phenoxy)propyl...)
Affinity DataKi:  29nMAssay Description:Determination of equilibrium dissociation constant Kd of radioligand: Membrane prepared as described above was pre-incubated with PVT-WGA SPA beads (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent