BDBM707067 (R)-7-(2-Methyl-2-(4- (trifluoromethyl)phenoxy)propyl)- 2-thia-7-azaspiro[4.4]nonane 2,2-dioxide (S)-7-(2-Methyl-2-(4- (trifluoromethyl)phenoxy)propyl)- 2-thia-7-azaspiro[4.4]nonane 2,2-dioxide::US20240400579, Example 141A

SMILES CC(C)(CN1CC[C@@]2(CCS(=O)(=O)C2)C1)Oc1ccc(C(F)(F)F)cc1

InChI Key InChIKey=RAGFTCRJLOBGFC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 707067   

LigandPNGBDBM707067((R)-7-(2-Methyl-2-(4- (trifluoromethyl)phenoxy)pro...)
Affinity DataKi:  25.6nMAssay Description:Compounds were prepared in a 96-well U bottom plate using an Echo550 machine and 10 mM compound DMSO stock solution, followed by an 8-dose 5-fold ser...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent

TargetEmopamil-binding protein-like(Human)
Genentech

US Patent
LigandPNGBDBM707067((R)-7-(2-Methyl-2-(4- (trifluoromethyl)phenoxy)pro...)
Affinity DataKi:  44nMAssay Description:Determination of equilibrium dissociation constant Kd of radioligand: Membrane prepared as described above was pre-incubated with PVT-WGA SPA beads (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent