BDBM707069 6-(2-Fluoro-3-(4- (trifluoromethyl)phenyl)propyl)- 2-thia-6-azaspiro[3.4]octane 2,2- dioxide::US20240400579, Example 142

SMILES O=S1(=O)CC2(CCN(CC(F)Cc3ccc(C(F)(F)F)cc3)C2)C1

InChI Key InChIKey=UFPMLEKRTZKZJS-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 707069   

LigandPNGBDBM707069(6-(2-Fluoro-3-(4- (trifluoromethyl)phenyl)propyl)-...)
Affinity DataKi:  16.1nMAssay Description:Compounds were prepared in a 96-well U bottom plate using an Echo550 machine and 10 mM compound DMSO stock solution, followed by an 8-dose 5-fold ser...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent

TargetEmopamil-binding protein-like(Human)
Genentech

US Patent
LigandPNGBDBM707069(6-(2-Fluoro-3-(4- (trifluoromethyl)phenyl)propyl)-...)
Affinity DataKi:  35nMAssay Description:Determination of equilibrium dissociation constant Kd of radioligand: Membrane prepared as described above was pre-incubated with PVT-WGA SPA beads (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent