BDBM707075 (S)-7-(2,2-Dimethyl-3-(6- (trifluoromethyl)pyridin-3- yl)propyl)-2-thia-7- azaspiro[4.4]nonane 2,2-dioxide (R)-7-(2,2-Dimethyl-3-(6- (trifluoromethyl)pyridin-3- yl)propyl)-2-thia-7- azaspiro[4.4]nonane 2,2-dioxide::US20240400579, Example 148B

SMILES CC(C)(Cc1ccc(C(F)(F)F)nc1)CN1CC[C@@]2(CCS(=O)(=O)C2)C1

InChI Key InChIKey=QXXWSUFLQLHZJM-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 707075   

LigandPNGBDBM707075((S)-7-(2,2-Dimethyl-3-(6- (trifluoromethyl)pyridin...)
Affinity DataKi:  28.6nMAssay Description:Compounds were prepared in a 96-well U bottom plate using an Echo550 machine and 10 mM compound DMSO stock solution, followed by an 8-dose 5-fold ser...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent

TargetEmopamil-binding protein-like(Human)
Genentech

US Patent
LigandPNGBDBM707075((S)-7-(2,2-Dimethyl-3-(6- (trifluoromethyl)pyridin...)
Affinity DataKi:  32nMAssay Description:Determination of equilibrium dissociation constant Kd of radioligand: Membrane prepared as described above was pre-incubated with PVT-WGA SPA beads (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent