BDBM707088 6-((1-((6- (Trifluoromethyl)pyridin-3- yl)methyl)cyclopropyl)methyl)- 2-thia-6-azaspiro[3.4]octane 2,2- dioxide::US20240400579, Example 157

SMILES O=S1(=O)CC2(CCN(CC3(Cc4ccc(C(F)(F)F)nc4)CC3)C2)C1

InChI Key InChIKey=PQODYOHBXJMCJC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 707088   

LigandPNGBDBM707088(6-((1-((6- (Trifluoromethyl)pyridin-3- yl)methyl)c...)
Affinity DataKi:  17.2nMAssay Description:Compounds were prepared in a 96-well U bottom plate using an Echo550 machine and 10 mM compound DMSO stock solution, followed by an 8-dose 5-fold ser...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent

TargetEmopamil-binding protein-like(Human)
Genentech

US Patent
LigandPNGBDBM707088(6-((1-((6- (Trifluoromethyl)pyridin-3- yl)methyl)c...)
Affinity DataKi:  25nMAssay Description:Determination of equilibrium dissociation constant Kd of radioligand: Membrane prepared as described above was pre-incubated with PVT-WGA SPA beads (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent