BDBM707115 (R)-7-(2-methyl-3-(2- (trifluoromethyl)pyrimidin-5- yl)propyl)-2-thia-7- azaspiro[3.5]nonane 2,2-dioxide::US20240400579, Example 215B

SMILES C[C@H](Cc1cnc(C(F)(F)F)nc1)CN1CCC2(CC1)CS(=O)(=O)C2

InChI Key InChIKey=NKNFSXKYQWDEJN-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 707115   

TargetEmopamil-binding protein-like(Human)
Genentech

US Patent
LigandPNGBDBM707115((R)-7-(2-methyl-3-(2- (trifluoromethyl)pyrimidin-5...)
Affinity DataKi:  25nMAssay Description:Determination of equilibrium dissociation constant Kd of radioligand: Membrane prepared as described above was pre-incubated with PVT-WGA SPA beads (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent

LigandPNGBDBM707115((R)-7-(2-methyl-3-(2- (trifluoromethyl)pyrimidin-5...)
Affinity DataKi:  136nMAssay Description:Compounds were prepared in a 96-well U bottom plate using an Echo550 machine and 10 mM compound DMSO stock solution, followed by an 8-dose 5-fold ser...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent