BDBM707139 7-(2-((6- (Trifluoromethyl)pyridin-3- yl)oxy)ethyl)-2-thia-7- azaspiro[3.5]nonane 2,2-dioxide::US20240400579, Example 230

SMILES O=S1(=O)CC2(CCN(CCOc3ccc(C(F)(F)F)nc3)CC2)C1

InChI Key InChIKey=VXIFCBUEUXXDQE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 707139   

TargetEmopamil-binding protein-like(Human)
Genentech

US Patent
LigandPNGBDBM707139(7-(2-((6- (Trifluoromethyl)pyridin-3- yl)oxy)ethyl...)
Affinity DataKi:  22nMAssay Description:Determination of equilibrium dissociation constant Kd of radioligand: Membrane prepared as described above was pre-incubated with PVT-WGA SPA beads (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent

LigandPNGBDBM707139(7-(2-((6- (Trifluoromethyl)pyridin-3- yl)oxy)ethyl...)
Affinity DataKi:  749nMAssay Description:Compounds were prepared in a 96-well U bottom plate using an Echo550 machine and 10 mM compound DMSO stock solution, followed by an 8-dose 5-fold ser...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent