BDBM707298 US12162878, Compound 184

SMILES Cn5cc(c1cc(S(C)(=O)=O)ccc1N2CCC3(CC2)CC3(F)F)c4C=CCc4c5=O

InChI Key InChIKey=MFKPAAFGGBINQO-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 707298   

TargetBromodomain-containing protein 2(Human)
Hinova Pharmaceuticals

US Patent
LigandPNGBDBM707298(US12162878, Compound 184)
Affinity DataIC50: 2nMAssay Description:The compounds were screened in vitro, and each compound was serially diluted to 10 concentrations. Four proteins BRD4 (D1+D2), BRDT (D1), BRD2 (D1+D2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetBromodomain-containing protein 3(Human)
Hinova Pharmaceuticals

US Patent
LigandPNGBDBM707298(US12162878, Compound 184)
Affinity DataIC50: 4.70nMAssay Description:The compounds were screened in vitro, and each compound was serially diluted to 10 concentrations. Four proteins BRD4 (D1+D2), BRDT (D1), BRD2 (D1+D2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Hinova Pharmaceuticals

US Patent
LigandPNGBDBM707298(US12162878, Compound 184)
Affinity DataIC50: 6.90nMAssay Description:The compounds were screened in vitro, and each compound was serially diluted to 10 concentrations. Four proteins BRD4 (D1+D2), BRDT (D1), BRD2 (D1+D2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetBromodomain testis-specific protein(Human)
Hinova Pharmaceuticals

US Patent
LigandPNGBDBM707298(US12162878, Compound 184)
Affinity DataIC50: 19nMAssay Description:The compounds were screened in vitro, and each compound was serially diluted to 10 concentrations. Four proteins BRD4 (D1+D2), BRDT (D1), BRD2 (D1+D2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent