BDBM707303 US12162836, Compound NASMP-09

SMILES CC(=O)N1CCC(CS(=O)(=O)c2ccc(-c3c(F)cccc3F)cc2)CC1

InChI Key InChIKey=FAXWWBHRULZCQE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 707303   

TargetCytochrome P450 2C19(Human)
Modern Biosciences

US Patent
LigandPNGBDBM707303(US12162836, Compound NASMP-09)
Affinity DataIC50: 1.78E+4nMAssay Description:CYP450 enzymes (final protein 75 pmol/mL for CYP1A2; 12.5 pmol/mL for CYP2C19; and 25 pmol/mL for CYP2C9, 2D6 and 3A4), 0.1 M phosphate buffer pH 7.4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Modern Biosciences

US Patent
LigandPNGBDBM707303(US12162836, Compound NASMP-09)
Affinity DataIC50: 4.45E+4nMAssay Description:CYP450 enzymes (final protein 75 pmol/mL for CYP1A2; 12.5 pmol/mL for CYP2C19; and 25 pmol/mL for CYP2C9, 2D6 and 3A4), 0.1 M phosphate buffer pH 7.4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Modern Biosciences

US Patent
LigandPNGBDBM707303(US12162836, Compound NASMP-09)
Affinity DataIC50: 5.00E+4nMAssay Description:CYP450 enzymes (final protein 75 pmol/mL for CYP1A2; 12.5 pmol/mL for CYP2C19; and 25 pmol/mL for CYP2C9, 2D6 and 3A4), 0.1 M phosphate buffer pH 7.4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Modern Biosciences

US Patent
LigandPNGBDBM707303(US12162836, Compound NASMP-09)
Affinity DataIC50: 5.00E+4nMAssay Description:CYP450 enzymes (final protein 75 pmol/mL for CYP1A2; 12.5 pmol/mL for CYP2C19; and 25 pmol/mL for CYP2C9, 2D6 and 3A4), 0.1 M phosphate buffer pH 7.4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetCytochrome P450 2C9(Human)
Modern Biosciences

US Patent
LigandPNGBDBM707303(US12162836, Compound NASMP-09)
Affinity DataIC50: 5.00E+4nMAssay Description:CYP450 enzymes (final protein 75 pmol/mL for CYP1A2; 12.5 pmol/mL for CYP2C19; and 25 pmol/mL for CYP2C9, 2D6 and 3A4), 0.1 M phosphate buffer pH 7.4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent