BDBM708084 1-((2-((R)-1-(3,4-dichlorobenzoyl)piperidin-3-yl)-4-(isoxazol-4-ylcarbamoyl)-1-methyl-6-oxo-1,6-dihydropyrimidin-5-yl)oxy)ethyl ethyl carbonate::US12172990, Example 131

SMILES CCOC(=O)OC(C)Oc1c(C(=O)NC2C=NOC2)nc([C@@H]2CCCN(C(=O)c3ccc(Cl)c(Cl)c3)C2)n(C)c1=O

InChI Key InChIKey=VGJHTGBVQVDRTQ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 708084   

TargetThree-prime repair exonuclease 1(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM708084(1-((2-((R)-1-(3,4-dichlorobenzoyl)piperidin-3-yl)-...)
Affinity DataIC50: 10nMAssay Description:Compound potency was assessed through a fluorescence assay measuring degradation of a custom dsDNA substrate possessing a fluorophore-quencher pair o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
US Patent

TargetThree prime repair exonuclease 2(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM708084(1-((2-((R)-1-(3,4-dichlorobenzoyl)piperidin-3-yl)-...)
Affinity DataIC50: 10nMAssay Description:Compound potency was assessed through a fluorescence assay measuring degradation of a custom dsDNA substrate possessing a fluorophore-quencher pair o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
US Patent