BDBM708389 3-amino-N-(1-(2-(2,4- difluorophenyl)-2-hydroxy-3- (1H-1,2,4-triazol-1- yl)propyl)piperidin-4-yl)-1-(4- methyl-3-phenoxyphenyl)-2- oxo-1,2-dihydrothieno[2,3- b]pyrazine-6-carboxamide::US20240424113, Compound I-12

SMILES Cc1ccc(-n2c(=O)c(N)nc3sc(C(=O)NC4CCN(CC(O)(Cn5cncn5)c5ccc(F)cc5F)CC4)cc32)cc1Oc1ccccc1

InChI Key InChIKey=HKZSGPWTRGOAMK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 708389   

TargetHeat shock protein 90 homolog(Yeast)
Bright Angel Therapeutics

US Patent
LigandPNGBDBM708389(3-amino-N-(1-(2-(2,4- difluorophenyl)-2-hydroxy-3-...)
Affinity DataKd:  146nMAssay Description:Surface Plasmon Resonance (SPR) Experiments. SPR experiments were performed on a Biacore S200 instrument at 25° C. Biotinylated Hsp90 Nuclear Binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetHeat shock protein 90(Neosartorya fumigata)
Bright Angel Therapeutics

US Patent
LigandPNGBDBM708389(3-amino-N-(1-(2-(2,4- difluorophenyl)-2-hydroxy-3-...)
Affinity DataKd:  431nMAssay Description:Surface Plasmon Resonance (SPR) Experiments. SPR experiments were performed on a Biacore S200 instrument at 25° C. Biotinylated Hsp90 Nuclear Binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent