BDBM708399 N-(((3S,5S)-5-((1H-1,2,4- triazol-1-yl)methyl)-5-(2,4- difluorophenyl)tetrahydrofuran- 3-yl)methyl)-3-amino-2-oxo-1- (4-phenyl-3,4-dihydro-2H- benzo[b][1,4]oxazin-6-yl)-1,2- dihydrothieno[2,3-b]pyrazine- 6-carboxamide::US20240424113, Compound I-27

SMILES Nc1nc2sc(C(=O)NC[C@H]3CO[C@](Cn4cncn4)(c4ccc(F)cc4F)C3)cc2n(-c2ccc3c(c2)N(c2ccccc2)CCO3)c1=O

InChI Key InChIKey=VFHXSANQRDREJZ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 708399   

TargetHeat shock protein 90 homolog(Yeast)
Bright Angel Therapeutics

US Patent
LigandPNGBDBM708399(N-(((3S,5S)-5-((1H-1,2,4- triazol-1-yl)methyl)-5-(...)
Affinity DataKd:  9.20nMAssay Description:Surface Plasmon Resonance (SPR) Experiments. SPR experiments were performed on a Biacore S200 instrument at 25° C. Biotinylated Hsp90 Nuclear Binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetHeat shock protein 90(Neosartorya fumigata)
Bright Angel Therapeutics

US Patent
LigandPNGBDBM708399(N-(((3S,5S)-5-((1H-1,2,4- triazol-1-yl)methyl)-5-(...)
Affinity DataKd:  13.4nMAssay Description:Surface Plasmon Resonance (SPR) Experiments. SPR experiments were performed on a Biacore S200 instrument at 25° C. Biotinylated Hsp90 Nuclear Binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent