BDBM708402 N-(1-((5-((1H-1,2,4-triazol-1- yl)methyl)-5-(2,4- difluorophenyl)tetrahydrofuran- 3-yl)methyl)piperidin-4-yl)-3- amino-2-oxo-1-(4-phenyl-3,4- dihydro-2H- benzo[b][1,4]oxazin-6-yl)-1,2- dihydrothieno[2,3-b]pyrazine- 6-carboxamide::US20240424113, Compound I-32

SMILES Nc1nc2sc(C(=O)NC3CCN(CC4COC(Cn5cncn5)(c5ccc(F)cc5F)C4)CC3)cc2n(-c2ccc3c(c2)N(c2ccccc2)CCO3)c1=O

InChI Key InChIKey=DUJZVANLFTYPFT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 708402   

TargetHeat shock protein 90 homolog(Yeast)
Bright Angel Therapeutics

US Patent
LigandPNGBDBM708402(N-(1-((5-((1H-1,2,4-triazol-1- yl)methyl)-5-(2,4- ...)
Affinity DataKd:  3.60nMAssay Description:Surface Plasmon Resonance (SPR) Experiments. SPR experiments were performed on a Biacore S200 instrument at 25° C. Biotinylated Hsp90 Nuclear Binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetHeat shock protein 90(Neosartorya fumigata)
Bright Angel Therapeutics

US Patent
LigandPNGBDBM708402(N-(1-((5-((1H-1,2,4-triazol-1- yl)methyl)-5-(2,4- ...)
Affinity DataKd:  50.5nMAssay Description:Surface Plasmon Resonance (SPR) Experiments. SPR experiments were performed on a Biacore S200 instrument at 25° C. Biotinylated Hsp90 Nuclear Binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent