BDBM708411 3-amino-N-(1-(2-(2,4- difluorophenyl)-2-hydroxy-3- (1H-1,2,4-triazol-1- yl)propyl)piperidin-4-yl)-7-(1- hydroxyethyl)-2-oxo-1-(1- phenyl-1H-indol-6-yl)-1,2- dihydrothieno[2,3-b]pyrazine- 6-carboxamide::US20240424113, Compound I-56

SMILES CC(O)c1c(C(=O)NC2CCN(CC(O)(Cn3cncn3)c3ccc(F)cc3F)CC2)sc2nc(N)c(=O)n(-c3ccc4ccn(-c5ccccc5)c4c3)c12

InChI Key InChIKey=SGTHFCPCPGVQPG-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 708411   

TargetHeat shock protein 90 homolog(Yeast)
Bright Angel Therapeutics

US Patent
LigandPNGBDBM708411(3-amino-N-(1-(2-(2,4- difluorophenyl)-2-hydroxy-3-...)
Affinity DataKd:  64.6nMAssay Description:Surface Plasmon Resonance (SPR) Experiments. SPR experiments were performed on a Biacore S200 instrument at 25° C. Biotinylated Hsp90 Nuclear Binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetHeat shock protein 90(Neosartorya fumigata)
Bright Angel Therapeutics

US Patent
LigandPNGBDBM708411(3-amino-N-(1-(2-(2,4- difluorophenyl)-2-hydroxy-3-...)
Affinity DataKd:  229nMAssay Description:Surface Plasmon Resonance (SPR) Experiments. SPR experiments were performed on a Biacore S200 instrument at 25° C. Biotinylated Hsp90 Nuclear Binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent