BDBM708472 (E)-4- (Dimethylamino)-N- [2-(2-ethoxy-4,6- dihydroxy-3- methyl- benzoyl)isoindolin- 4-yl]but-2-enamide::US20240425453, Example 22

SMILES CCOc1c(C)c(O)cc(O)c1C(=O)N1Cc2cccc(NC(=O)/C=C/CN(C)C)c2C1

InChI Key InChIKey=KVYRWUUCWBRPDO-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 708472   

TargetMismatch repair endonuclease PMS2(Human)
Neophore

US Patent
LigandPNGBDBM708472((E)-4- (Dimethylamino)-N- [2-(2-ethoxy-4,6- dihydr...)
Affinity DataIC50: 100nMAssay Description:Test compounds, as 10 mM DMSO stocks, were dispensed into a Black Fluotrac 200 384 well medium binding plate (Greiner Bio-One, item number 781076) us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent