BDBM708473 (E)-N-[2-[4,6- Dihydroxy-3- methyl-2-(2,2,2- trifluoroethoxy)ben- zoyl]isoindolin-4- yl]-4- (dimethylamino)but- 2-enamide::US20240425453, Example 23

SMILES Cc1c(O)cc(O)c(C(=O)N2Cc3cccc(NC(=O)/C=C/CN(C)C)c3C2)c1OCC(F)(F)F

InChI Key InChIKey=DJKGCSYROPFIQG-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 708473   

TargetMismatch repair endonuclease PMS2(Human)
Neophore

US Patent
LigandPNGBDBM708473((E)-N-[2-[4,6- Dihydroxy-3- methyl-2-(2,2,2- trifl...)
Affinity DataIC50: 100nMAssay Description:Test compounds, as 10 mM DMSO stocks, were dispensed into a Black Fluotrac 200 384 well medium binding plate (Greiner Bio-One, item number 781076) us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent