BDBM708481 (E)-N-[2-[2- (Cyclopropylmetho- xy)-4,6-dihydroxy- 3-methyl- benzoyl]isoindolin- 4-yl]-4- (dimethylamino)-N- methyl-but-2- enamide::US20240425453, Example 31

SMILES Cc1c(O)cc(O)c(C(=O)N2Cc3cccc(N(C)C(=O)/C=C/CN(C)C)c3C2)c1OCC1CC1

InChI Key InChIKey=GFLIBEHDKSYKAV-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 708481   

TargetMismatch repair endonuclease PMS2(Human)
Neophore

US Patent
LigandPNGBDBM708481((E)-N-[2-[2- (Cyclopropylmetho- xy)-4,6-dihydroxy-...)
Affinity DataIC50: 550nMAssay Description:Test compounds, as 10 mM DMSO stocks, were dispensed into a Black Fluotrac 200 384 well medium binding plate (Greiner Bio-One, item number 781076) us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent