BDBM708575 (S)-4-methyl-3-(1-(2- ((1-methyl-1H- pyrazol-4- yl)amino)pyrimidin-5- yl)pyrrolidin-3-yl)-N- (3- (trifluoromethyl) phenyl)benzamide::US20240425482, Example 48

SMILES Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1[C@@H]1CCN(c2cnc(Nc3cnn(C)c3)nc2)C1

InChI Key InChIKey=NISMMMPKYSODTN-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 708575   

TargetEpithelial discoidin domain-containing receptor 1(Human)
Chiesi Farmaceutici

US Patent
LigandChemical structure of BindingDB Monomer ID 708575BDBM708575((S)-4-methyl-3-(1-(2- ((1-methyl-1H- pyrazol-4- yl...)
Affinity DataKi: <10nMAssay Description:DDR1 and DDR2 binding assays were performed using Life Technologies LanthaScreen™ Europium Kinase Binding assay. The compounds were incubated with 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetDiscoidin domain-containing receptor 2(Human)
Chiesi Farmaceutici

US Patent
LigandChemical structure of BindingDB Monomer ID 708575BDBM708575((S)-4-methyl-3-(1-(2- ((1-methyl-1H- pyrazol-4- yl...)
Affinity DataKi: <10nMAssay Description:DDR1 and DDR2 binding assays were performed using Life Technologies LanthaScreen™ Europium Kinase Binding assay. The compounds were incubated with 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent