BDBM708696 US20240425497, Example 24

SMILES C[C@H]1CCCN(Cc2cc3c(C#N)cn(-c4cncc(-c5ccc(F)cc5C(=O)N5CC(F)C5)c4)c(=O)c3[nH]2)C1

InChI Key InChIKey=HNTBSHAJVKEDGY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 708696   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Arcus Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 708696BDBM708696(US20240425497, Example 24)
Affinity DataIC50: 550nMAssay Description:The assays were performed in assay buffer consisting of 20 mM Hepes, 150 mM NaCl, 0.01% Triton X-100, 0.5 mM TCEP, 0.01% BSA. On the day of the assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent