BDBM709037 (S)-7'-(3,5- difluorophenyl)-1- (2,3,5- trifluorobenzoyl) dihydro- 1'H,3'H,5'H- spiro[piperidine-4,2'- pyrazolo[1,2- a]pyrazol]-l'-one::US20240425524, Example 4.12

SMILES O=C(c1cc(F)cc(F)c1F)N1CCC2(CC1)CN1CC[C@@H](c3cc(F)cc(F)c3)N1C2=O

InChI Key InChIKey=UMEYRHGVMUGWNR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 709037   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 709037BDBM709037((S)-7'-(3,5- difluorophenyl)-1- (2,3,5- trifluorob...)
Affinity DataEC50:  26nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution: top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent