BDBM709800 (5'S,7a'R)-5'-cyclohexyl- 1-(3-fluoropyrazolo [1,5-a]pyrimidin-7- yl)tetrahydro-3'H- spiro[piperidine-4,2'- pyrrolo[2,1-b]oxazol]-3'- one, TFA salt::US12180226, Example 4.87

SMILES O=C1N2[C@@H](CC[C@H]2C2CCCCC2)OC12CCN(c1ccnc3c(F)cnn13)CC2

InChI Key InChIKey=HGSTZQMQGWMOND-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 709800   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 709800BDBM709800((5'S,7a'R)-5'-cyclohexyl- 1-(3-fluoropyrazolo [1,5...)
Affinity DataEC50: <2.50E+4nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
US Patent