BDBM709816 (5''S,7a''R)-5''-(2- fluorophenyl)-1-(3- fluoropyrazolo[1,5-a] pyrimidin-7- yl)tetrahydro-3''H- spiro[piperidine-4,2''- pyrrolo[2,1-b]oxazol]-3''- one::US12180226, Example 4.102

SMILES O=C1N2[C@@H](CC[C@H]2c2ccccc2F)OC12CCN(c1ccnc3c(F)cnn13)CC2

InChI Key InChIKey=DWJJKBAGBKXOGG-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 709816   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM709816((5'S,7a'R)-5'-(2- fluorophenyl)-1-(3- fluoropyrazo...)
Affinity DataEC50: <2.50E+4nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
US Patent