BDBM710312 (5''S,7a''R)-1- ([1,2,4]triazolo[1,5- a]pyridin-5-yl)-5''-(2- fluorophenyl)tetrahydro- 3''H-spiro[azetidine- 3,2''-pyrrolo[2,1- b]oxazol]-3''-one, TFA salt::US12180226, Example 13.20

SMILES O=C1N2[C@@H](CC[C@H]2c2ccccc2F)OC12CN(c1cccc3ncnn13)C2

InChI Key InChIKey=VIXLTFPTLJPBHC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 710312   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM710312((5'S,7a'R)-1- ([1,2,4]triazolo[1,5- a]pyridin-5-yl...)
Affinity DataEC50:  2.49E+4nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
US Patent