BDBM710581 US12187701, Compound FMF-04-012-2

SMILES CN(C)C/C=C/C(=O)Nc1ccc(C(=O)Nc2ccc(NC(=O)c3n[nH]cc3NC(=O)c3c(Cl)cccc3Cl)cc2)cc1

InChI Key InChIKey=RYCOMKGMIRGGDD-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 710581   

TargetCyclin-dependent kinase 2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM710581(US12187701, Compound FMF-04-012-2)
Affinity DataIC50: 52.8nMAssay Description:Lanthascreen Eu kinase binding assays were conducted for Cdk14/CycY largely as performed in the commercial assay service by Life Technologies, but in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 14(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM710581(US12187701, Compound FMF-04-012-2)
Affinity DataIC50: 68nMAssay Description:Lanthascreen Eu kinase binding assays were conducted for Cdk14/CycY largely as performed in the commercial assay service by Life Technologies, but in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 16(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM710581(US12187701, Compound FMF-04-012-2)
Affinity DataIC50: 111nMAssay Description:Lanthascreen Eu kinase binding assays were conducted for Cdk14/CycY largely as performed in the commercial assay service by Life Technologies, but in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 14(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM710581(US12187701, Compound FMF-04-012-2)
Affinity DataIC50: 560nMAssay Description:Lanthascreen Eu kinase binding assays were conducted for Cdk14/CycY largely as performed in the commercial assay service by Life Technologies, but in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent