BDBM710629 US12187701, Compound FMF-05-033-1

SMILES CCC(=O)Nc4cccc(S(=O)(=O)N3CCC(NC(=O)c1n[nH]cc1NC(=O)c2c(Cl)cccc2OC)CC3)c4

InChI Key InChIKey=BQCPUBPCBQLKPP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 710629   

TargetCyclin-dependent kinase 14(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM710629(US12187701, Compound FMF-05-033-1)
Affinity DataIC50: 0.800nMAssay Description:Lanthascreen Eu kinase binding assays were conducted for Cdk14/CycY largely as performed in the commercial assay service by Life Technologies, but in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM710629(US12187701, Compound FMF-05-033-1)
Affinity DataIC50: 3nMAssay Description:Lanthascreen Eu kinase binding assays were conducted for Cdk14/CycY largely as performed in the commercial assay service by Life Technologies, but in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 16(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM710629(US12187701, Compound FMF-05-033-1)
Affinity DataIC50: 3.40nMAssay Description:Lanthascreen Eu kinase binding assays were conducted for Cdk14/CycY largely as performed in the commercial assay service by Life Technologies, but in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 14(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM710629(US12187701, Compound FMF-05-033-1)
Affinity DataIC50: 135nMAssay Description:Lanthascreen Eu kinase binding assays were conducted for Cdk14/CycY largely as performed in the commercial assay service by Life Technologies, but in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent