BDBM710640 US12187701, Compound IHK-01-013-2

SMILES COc1cccc(F)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCN(Cc2cccc(NC(=O)/C=C/CN(C)C)c2)CC1

InChI Key InChIKey=JIBHJLIMQZDZRK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 710640   

TargetCyclin-dependent kinase 14(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM710640(US12187701, Compound IHK-01-013-2)
Affinity DataIC50: 4.20nMAssay Description:Lanthascreen Eu kinase binding assays were conducted for Cdk14/CycY largely as performed in the commercial assay service by Life Technologies, but in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 16(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM710640(US12187701, Compound IHK-01-013-2)
Affinity DataIC50: 7.40nMAssay Description:Lanthascreen Eu kinase binding assays were conducted for Cdk14/CycY largely as performed in the commercial assay service by Life Technologies, but in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM710640(US12187701, Compound IHK-01-013-2)
Affinity DataIC50: 53nMAssay Description:Lanthascreen Eu kinase binding assays were conducted for Cdk14/CycY largely as performed in the commercial assay service by Life Technologies, but in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent