BDBM710705 2-(6-(cyclopentyloxy)-4-((1r,3r)-3-methyl- 1-(4-methyl-4H-1,2,4-triazol-3- yl)cyclobutyl)pyridin-2-yl)-6-(((1- methylcyclobutyl)amino)methyl)-4- (trifluoromethyl)isoindolin-1-one::US12187709, Compound 55

SMILES Cn1cnnc1[C@]1(c2cc(OC3CCCC3)nc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)C[C@@H](C)C1

InChI Key InChIKey=BNHYZCBZOBOXAW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 710705   

LigandChemical structure of BindingDB Monomer ID 710705BDBM710705(2-(6-(cyclopentyloxy)-4-((1r,3r)-3-methyl- 1-(4-me...)
Affinity DataIC50: 6.70nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710705BDBM710705(2-(6-(cyclopentyloxy)-4-((1r,3r)-3-methyl- 1-(4-me...)
Affinity DataIC50: 9.40nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent