BDBM710709 2-(4-(3,3-difluoro-1-(4-methyl-4H-1,2,4- triazol-3-yl)cyclobutyl)-6-ethylpyridin-2-yl)- 6-(((1-methylcyclobutyl)amino)methyl)-4- (trifluoromethyl)isoindolin-1-one::US12187709, Compound 59

SMILES CCc1cc(C2(c3nncn3C)CC(F)(F)C2)cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)n1

InChI Key InChIKey=JHIHXRUQWAQQLG-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 710709   

LigandChemical structure of BindingDB Monomer ID 710709BDBM710709(2-(4-(3,3-difluoro-1-(4-methyl-4H-1,2,4- triazol-3...)
Affinity DataIC50: 17nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710709BDBM710709(2-(4-(3,3-difluoro-1-(4-methyl-4H-1,2,4- triazol-3...)
Affinity DataIC50: 18nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent