BDBM710763 (S)-2-(3-((4-methyl-4H-1,2,4-triazol-3- yl)(2-oxaspiro[3.3]heptan-6- yl)methyl)phenyl)-6-(((1- methylcyclobutyl)amino)methyl)-4- (trifluoromethyl)isoindolin-1-one::US12187709, Compound 121

SMILES Cn1cnnc1[C@H](c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)C1CC2(COC2)C1

InChI Key InChIKey=ATRQDYDDZPIIEJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 710763   

LigandChemical structure of BindingDB Monomer ID 710763BDBM710763((S)-2-(3-((4-methyl-4H-1,2,4-triazol-3- yl)(2-oxas...)
Affinity DataIC50: 1.10E+4nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710763BDBM710763((S)-2-(3-((4-methyl-4H-1,2,4-triazol-3- yl)(2-oxas...)
Affinity DataIC50: 2.00E+4nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent