BDBM710957 2-(3-((S)-(4-methyl-4H-1,2,4-triazol-3- yl)(oxetan-3-yl)methyl)phenyl)-6-((S)-1-((1- methylcyclobutyl)amino)propyl)-4- (trifluoromethyl)isoindolin-1-one::US12187709, Compound 315

SMILES CC[C@H](NC1(C)CCC1)c1cc2c(c(C(F)(F)F)c1)CN(c1cccc([C@@H](c3nncn3C)C3COC3)c1)C2=O

InChI Key InChIKey=KHUHMPCMKSWRNR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 710957   

LigandChemical structure of BindingDB Monomer ID 710957BDBM710957(2-(3-((S)-(4-methyl-4H-1,2,4-triazol-3- yl)(oxetan...)
Affinity DataIC50: 6.80E+3nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710957BDBM710957(2-(3-((S)-(4-methyl-4H-1,2,4-triazol-3- yl)(oxetan...)
Affinity DataIC50: 2.00E+4nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent