BDBM711047 4-(difluoromethyl)-2-(3-((S)-(4-methyl-4H- 1,2,4-triazol-3-yl)(oxetan-3- yl)methyl)phenyl)-6-((R)-1-((1- methylcyclobutyl)amino)ethyl)isoindolin-1- one::US12187709, Compound 406

SMILES C[C@@H](NC1(C)CCC1)c1cc2c(c(C(F)F)c1)CN(c1cccc([C@@H](c3nncn3C)C3COC3)c1)C2=O

InChI Key InChIKey=ZEYDBVDHJVJKOI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 711047   

LigandChemical structure of BindingDB Monomer ID 711047BDBM711047(4-(difluoromethyl)-2-(3-((S)-(4-methyl-4H- 1,2,4-t...)
Affinity DataIC50: 9.90E+3nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 711047BDBM711047(4-(difluoromethyl)-2-(3-((S)-(4-methyl-4H- 1,2,4-t...)
Affinity DataIC50: 2.00E+4nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent