BDBM711065 6-((2-hydroxy-7-azaspiro[3.5]nonan-7- yl)methyl)-2-(3-((1r,3r)-3-methoxy-1-(4- methyl-4H-1,2,4-triazol-3- yl)cyclobutyl)phenyl)-4- (trifluoromethyl)isoindolin-1-one::US12187709, Compound 424

SMILES CO[C@H]1C[C@](c2cccc(N3Cc4c(cc(CN5CCC6(CC5)CC(O)C6)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1

InChI Key InChIKey=PITQJZPACMYKJA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 711065   

LigandChemical structure of BindingDB Monomer ID 711065BDBM711065(6-((2-hydroxy-7-azaspiro[3.5]nonan-7- yl)methyl)-2...)
Affinity DataIC50: 230nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 711065BDBM711065(6-((2-hydroxy-7-azaspiro[3.5]nonan-7- yl)methyl)-2...)
Affinity DataIC50: 1.50E+3nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent