BDBM711120 2-(3-((1r,3r)-3-methoxy-1-(4-methyl-4H- 1,2,4-triazol-3-yl)cyclobutyl)phenyl)-6-(((3- methyloxetan-3-yl)amino)methyl)-4- (trifluoromethyl)isoindolin-1-one::US12187709, Compound 479

SMILES CO[C@H]1C[C@](c2cccc(N3Cc4c(cc(CNC5(C)COC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1

InChI Key InChIKey=JRWGRRAZERPDRL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 711120   

LigandChemical structure of BindingDB Monomer ID 711120BDBM711120(2-(3-((1r,3r)-3-methoxy-1-(4-methyl-4H- 1,2,4-tria...)
Affinity DataIC50: 29nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 711120BDBM711120(2-(3-((1r,3r)-3-methoxy-1-(4-methyl-4H- 1,2,4-tria...)
Affinity DataIC50: 250nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent