BDBM711479 (2R)-2-(5-Fluoro-2-methoxypyridin-4-yl)-1-[7-methyl-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydro-1H-spiro[1,8-naphthyridine-2,3''-pyrrolidin]-1''-yl]propan-1-one, DIAST-1 (16) and (2R)-2-(5-Fluoro-2-methoxypyridin-4-yl)-1-[7-methyl-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydro-1H-spiro[1,8-naphthyridine-2,3''-pyrrolidin]-1''-yl]propan-1-one, DIAST-2 (17)::US12187727, Example 16::US20250084084, Example 16

SMILES COc1cc([C@@H](C)C(=O)N2CC[C@@]3(CCc4cc(-c5cnn(C)c5)c(C)nc4N3)C2)c(F)cn1

InChI Key InChIKey=GDYXORJDLWGBMR-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 711479   

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM711479((2R)-2-(5-Fluoro-2-methoxypyridin-4-yl)-1-[7-methy...)
Affinity DataKi:  0.360nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/17/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM711479((2R)-2-(5-Fluoro-2-methoxypyridin-4-yl)-1-[7-methy...)
Affinity DataKi:  0.360nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent