BDBM711774 N-(2-(3-(Dimethylamino)propoxy)-5- (3''-methyl-2-oxo-2'',3''-dihydrospiro [cyclopropane-1,1''- pyrrolo[2,3-c]quinolin]-8''- yl)pyridin-3-yl)-4- (trifluoromethyl)benzenesulfonamide::US12187742, Example 108

SMILES CN(C)CCCOc1ncc(-c2ccc3ncc4c(c3c2)C2(CC2)C(=O)N4C)cc1NS(=O)(=O)c1ccc(C(F)(F)F)cc1

InChI Key InChIKey=WGPQOOKXSBMISP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 711774   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Xrad Therapeutics

US Patent
LigandPNGBDBM711774(N-(2-(3-(Dimethylamino)propoxy)-5- (3'-methyl-2-ox...)
Affinity DataIC50: 0.5nMAssay Description:On day one, coat 96-well plate (ThermoFisher. Cat #: 442404) with GST-p53 (1-101) peptide (purified by Pharmaron, BCS department) by diluting 3 μg of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent