BDBM711884 N-(2-(3-(Dimethylamino) propoxy)-5-(3''-methyl-2''- oxo-2'',3''-dihydrospiro [cyclobutane- 1,1''-pyrrolo[2,3-c] quinolin]-8''- yl)pyridin-3-yl)-1,1,1- trifluoromethane- sulfonamide::US12187742, Example 239

SMILES CN(C)CCCOc5ncc(c2ccc1ncc4c(c1c2)C3(CCC3)C(=O)N4C)cc5NS(=O)(=O)C(F)(F)F

InChI Key InChIKey=WEEIJHAKEWVFES-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 711884   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Xrad Therapeutics

US Patent
LigandPNGBDBM711884(N-(2-(3-(Dimethylamino) propoxy)-5-(3'-methyl-2'- ...)
Affinity DataIC50: 0.5nMAssay Description:On day one, coat 96-well plate (ThermoFisher. Cat #: 442404) with GST-p53 (1-101) peptide (purified by Pharmaron, BCS department) by diluting 3 μg of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent