BDBM711906 1-Cyano-N-(2-(3-(dimethylamino) propoxy)-5-(3''-methyl-2''-oxo-2'',3''- dihydrospiro[cyclobutane-1,1''-pyrrolo[2,3- c]quinolin]-8''-yl)pyridin-3- yl)methanesulfonamide::US12187742, Example 273

SMILES CN(C)CCOCc1ncc(-c2ccc3ncc4c(c3c2)C2(CCC2)C(=O)N4C)cc1NS(=O)(=O)CC#N

InChI Key InChIKey=QPVIUPCSFHXPOD-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 711906   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Xrad Therapeutics

US Patent
LigandPNGBDBM711906(1-Cyano-N-(2-(3-(dimethylamino) propoxy)-5-(3'-met...)
Affinity DataIC50: 0.5nMAssay Description:On day one, coat 96-well plate (ThermoFisher. Cat #: 442404) with GST-p53 (1-101) peptide (purified by Pharmaron, BCS department) by diluting 3 μg of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent