BDBM711943 N-(5-(3''-Methyl-2''-oxo-2'',3''- dihydrospiro[cyclobutane-1,1''- pyrrolo[2,3-c]quinolin]-8''-yl)- 2-(3-(methylamino)azetidin- 1-yl)pyridin-3-yl) methanesulfonamide formate::US12187742, Example 329

SMILES CNC1CN(c2ncc(-c3ccc4ncc5c(c4c3)C3(CCC3)C(=O)N5C)cc2NS(C)(=O)=O)C1

InChI Key InChIKey=GFVBUIRRZHNXSB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 711943   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Xrad Therapeutics

US Patent
LigandPNGBDBM711943(N-(5-(3'-Methyl-2'-oxo-2',3'- dihydrospiro[cyclobu...)
Affinity DataIC50: 0.5nMAssay Description:On day one, coat 96-well plate (ThermoFisher. Cat #: 442404) with GST-p53 (1-101) peptide (purified by Pharmaron, BCS department) by diluting 3 μg of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent