BDBM711984 cis-N-(5-(7''-Fluoro-3- (isopropoxymethyl)-3''-methyl-2''-oxo- 2'',3''-dihydrospiro[cyclobutane-1,1''- pyrrolo[2,3-c]quinolin]-8''-yl)-2- (2-(isopropylamino)ethoxy)pyridin-3- yl)methanesulfonamide::US12187742, Example 410

SMILES CC(C)NCCOc1ncc(-c2cc3c(cc2F)ncc2c3[C@]3(C[C@H](COC(C)C)C3)C(=O)N2C)cc1NS(C)(=O)=O

InChI Key InChIKey=MCFMGBMHTIGZGN-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 711984   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Xrad Therapeutics

US Patent
LigandPNGBDBM711984(cis-N-(5-(7'-Fluoro-3- (isopropoxymethyl)-3'-methy...)
Affinity DataIC50: 0.5nMAssay Description:On day one, coat 96-well plate (ThermoFisher. Cat #: 442404) with GST-p53 (1-101) peptide (purified by Pharmaron, BCS department) by diluting 3 μg of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent