BDBM712160 (4R)-4-Amino-1-[4-[4-[6-[difluoro(phenyl)methyl]-2-methyl-pyrimidin-4-yl]piperazin-1-yl]sulfonylphenyl]pyrrolidin-2-one::US20250011300, Example 83

SMILES Cc1nc(N2CCN(S(=O)(=O)c3ccc(N4C[C@H](N)CC4=O)cc3)CC2)cc(C(F)(F)c2ccccc2)n1

InChI Key InChIKey=VXDYGGRQUSBLDR-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 712160   

TargetUDP-2,3-diacylglucosamine hydrolase()
Hoffmann-La Roche

US Patent
LigandPNGBDBM712160((4R)-4-Amino-1-[4-[4-[6-[difluoro(phenyl)methyl]-2...)
Affinity DataIC50: 2nMAssay Description:The inhibitory potency of molecules to UDP-2,3-diacylglucosamine hydrolase (LpxH) was determined using the UMP/CMP-Glo™ Glycosyltransferase Assay kit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent