BDBM712175 4-Amino-1-[4-[4-[6-chloro-4-[difluoro(8-oxabicyclo[3.2.1]octan-3-yl)methyl]-2-pyridyl]piperazin-1-yl]sulfonylphenyl]pyrrolidin-2-one::US20250011300, Example 100

SMILES NC1CC(=O)N(c2ccc(S(=O)(=O)N3CCN(c4cc(C(F)(F)C5CC6CCC(C5)O6)cc(Cl)n4)CC3)cc2)C1

InChI Key InChIKey=BQHPXDHWOKOBQL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 712175   

TargetUDP-2,3-diacylglucosamine hydrolase()
Hoffmann-La Roche

US Patent
LigandPNGBDBM712175(4-Amino-1-[4-[4-[6-chloro-4-[difluoro(8-oxabicyclo...)
Affinity DataIC50: 2nMAssay Description:The inhibitory potency of molecules to UDP-2,3-diacylglucosamine hydrolase (LpxH) was determined using the UMP/CMP-Glo™ Glycosyltransferase Assay kit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent