BDBM712632 US12195462, Example 1

SMILES CN1C(=O)CN2c3c(cccc31)[C@@H]1CN(CCCOc3ccc(F)cc3)CC[C@@H]12

InChI Key InChIKey=IPUPPFQXCOAAGE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 712632   

Target5-hydroxytryptamine receptor 2A(Human)
Intra-Cellular Therapies

US Patent
LigandPNGBDBM712632(US12195462, Example 1)
Affinity DataKi:  3nMAssay Description:Receptor binding is determined for the Compounds of Examples 1, 2 and 3 (corresponding to Formula 1, Formula B and Formula A, respectively). The foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Intra-Cellular Therapies

US Patent
LigandPNGBDBM712632(US12195462, Example 1)
Affinity DataKi:  10.2nMAssay Description:Receptor binding is determined for the Compounds of Examples 1, 2 and 3 (corresponding to Formula 1, Formula B and Formula A, respectively). The foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Intra-Cellular Therapies

US Patent
LigandPNGBDBM712632(US12195462, Example 1)
Affinity DataKi:  40nMAssay Description:Receptor binding is determined for the Compounds of Examples 1, 2 and 3 (corresponding to Formula 1, Formula B and Formula A, respectively). The foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Intra-Cellular Therapies

US Patent
LigandPNGBDBM712632(US12195462, Example 1)
Affinity DataKi:  114nMAssay Description:Receptor binding is determined for the Compounds of Examples 1, 2 and 3 (corresponding to Formula 1, Formula B and Formula A, respectively). The foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Intra-Cellular Therapies

US Patent
LigandPNGBDBM712632(US12195462, Example 1)
Affinity DataKi: >1.00E+4nMAssay Description:Receptor binding is determined for the Compounds of Examples 1, 2 and 3 (corresponding to Formula 1, Formula B and Formula A, respectively). The foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent