BDBM712990 US20250019385, Example I-36

SMILES CCn1c(=O)n([C@@H]2CCCOC2)c2nc(-c3onc4c3CCC[C@@]43CCCc4sc(N)c(C#N)c43)nc(O[C@@H](C)C34CCCN3CCC4)c21

InChI Key InChIKey=XCBYCLSEIASADD-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 712990   

TargetGTPase KRas [1-169,G12C,C51S,C80L,C118S]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM712990(US20250019385, Example I-36)
Affinity DataIC50: 2nMAssay Description:This assay can be used to examine the potency with which compounds according to the invention binding to (mutated) KRAS inhibit the protein-protein i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetGTPase KRas [1-169,G12D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM712990(US20250019385, Example I-36)
Affinity DataIC50: 2nMAssay Description:This assay can be used to examine the potency with which compounds according to the invention binding to (mutated) KRAS inhibit the protein-protein i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent