BDBM713119 US12195427, Compound 2003::US12351648, Compound 2003

SMILES Cc1cccc(-c2nc3cc(C(=N)N)ccc3[nH]2)n1

InChI Key InChIKey=SIMKDFKQLHBDBE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 713119   

TargetMannan-binding lectin serine protease 2(Human)
Omeros

US Patent
LigandPNGBDBM713119(US12195427, Compound 2003 | US12351648, Compound 2...)
Affinity DataKi: <50nMAssay Description:The MASP-2 assay protocol was carried out as follows. Test compounds were serially diluted in DMSO and then 100 nL of each dilution was transferred t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetProthrombin(Human)
Omeros

US Patent
LigandPNGBDBM713119(US12195427, Compound 2003 | US12351648, Compound 2...)
Affinity DataKi:  1.50E+3nMAssay Description:The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetProthrombin(Human)
Omeros

US Patent
LigandPNGBDBM713119(US12195427, Compound 2003 | US12351648, Compound 2...)
Affinity DataKi: <2.50E+3nMAssay Description:The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent