BDBM713483 US20250019387, Table 1a.132

SMILES C=CC(=O)N1CC[C@@H](N(C)c2nc(OC[C@]34CCCN3C[C@@H](F)C4)nc3c2CCN(c2cccc4cccc(Cl)c24)C3)C1

InChI Key InChIKey=WMCBKLQRDLKWEG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 713483   

LigandPNGBDBM713483(US20250019387, Table 1a.132)
Affinity DataIC50: 500nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent