BDBM713595 US20250019387, Table 1a.323

SMILES CN(C)C/C=C/S(=O)(=O)CCN(C)c1nc(OCC23CCCN2CCC3)nc2c1CCN(c1cccc3cccc(Cl)c13)C2

InChI Key InChIKey=MYAFYRXRJAAYPQ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 713595   

LigandPNGBDBM713595(US20250019387, Table 1a.323)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent