BDBM714441 US20250025443, Compound 596::US20250025443, Example 476

SMILES COc1cc(C2(NC(=O)c3cc(OC[C@@]45CCCN4C[C@H](F)C5)ccc3C)CC2)c2cccnc2c1

InChI Key InChIKey=AOVBYLIMKSHTMG-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 714441   

TargetReplicase polyprotein 1a(2019-nCoV)
Clear Creek Bio

US Patent
LigandPNGBDBM714441(US20250025443, Compound 596 | US20250025443, Examp...)
Affinity DataIC50: 100nMAssay Description:Test compounds were assayed at 10 concentrations from 10 μM, in duplicate for the IC50 determination. The assay buffer contained 50 mM HEPES (pH 7.5)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent