BDBM715194 US20250026748, Compound 358

SMILES COC(=O)N1CCN(c2cc(-c3cc(C(F)F)ncc3OC)c(C(=O)Nc3nnc(C#CC4CC4)s3)cn2)C(=O)C1

InChI Key InChIKey=YASUKDVWPWQNRK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 715194   

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandPNGBDBM715194(US20250026748, Compound 358)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent